CABBI technologies can open the door to new tools and products for a number of large industries. As such, our teams works with our respective Office of Technology Management offices to commercialize our technologies and partner with industry.
A sampling of the filings can be found below. For current licensing status, please contact Celine Young at chyoung@illinois.edu.
2025 Filings
Invention Disclosure: “DayCent-CABBI Ecosystem Model.” Inventors: William Parton and Melannie Hartman, Colorado State University.
U.S. Provisional Patent Application: “Decompartmentalization of the Yeast Mitochondrial Metabolism to Improve Chemical Production in Issatechenchia orientalis.” Inventors: Huimin Zhao and Vinh Tran, University of Illinois Urbana-Champaign.
U.S. Provisional Patent Application: “Imaging and Gas Exchange Analysis in Plant Tissues.” Inventors: Andrew Leakey, Joseph Crawford, and Glenn Fried, University of Illinois Urbana-Champaign.
Invention Disclosure: “A Framework to Enable Automated Process Synthesis, Modeling, Simulation, and Evaluation under Uncertainty from User Natural Language Inputs by Distributing Expertise among Component Tools.” Inventors: Jeremy Guest, University of Illinois Urbana-Champaign.
Invention Disclosure: “A Photobiosynthesis Platform for Unnatural Biosynthesis by Integrating Photoenzymatic Reactions into Microbial Cells.” Inventors: Huimin Zhao, University of Illinois Urbana-Champaign.
Invention Disclosure: “Chromosomal Integration Sites for Stable Heterologous Gene Expression in Rhodotorula toruloides.” Inventors: Huimin Zhao, University of Illinois Urbana-Champaign.
Invention Disclosure: “DayCent-CABBI Ecosystem Model.” Inventors: Melannie Hartman and William Parton, Colorado State University.
Invention Disclosure: “Enhancing Lipid Production in Plant Cells through Automated High-throughput Genome Engineering and Phenotyping.” Inventors: Matt Hudson, University of Illinois Urbana-Champaign.
Invention Disclosure: “Improved Variants of Yersinia mollaretii phytase (YmPhytase) Enzyme.” Inventors: Huimin Zhao, University of Illinois Urbana-Champaign.
2024 Filings
Invention Disclosure: “A Generalized Platform for Artificial Intelligence-powered Autonomous Protein Engineering.” Inventors: Huimin Zhao, Stephan Lane, Nilmani Singh, and Tianhao Yu, University of Illinois Urbana-Champaign.
U.S. Non-Provisional Patent Application: “Sustainable Chemical-free Process for Recovery of Natural Pigments from Bioenergy Crops.” Inventors: Vijay Singh, Shivali Banerjee, and Erik Sacks, University of Illinois Urbana-Champaign.
Invention Disclosure: “InterBRC Data Products Portal.” Inventors: Leslie Stoecker, University of Illinois Urbana-Champaign and BRC collaborators.
Invention Disclosure: “Downstream Processing to Recover High-purity Crystal of 3-Hydroxy Propionic Acid (Alkali salt) from Low pH and Low Titer Fermentation Broth.” Inventors: Vijay Singh, University of Illinois Urbana-Champaign.
Invention Disclosure: “Generative Adversarial Network for Improved Classification of Label-Limited Training Datasets.” Inventors: Andrew Leakey, University of Illinois Urbana-Champaign.
Invention Disclosure: “Method for Production of Vegetative Oil-Rich Miscanthus.” Inventors: Kankshita Swaminathan, Ed Cahoon.
Invention Disclosure: “Rerouting Phosphoenolpyruvate in Sugar-rich Tissues Enables Increased Fatty Acid Biosynthesis.” Inventors: Li-Qing Chen, University of Illinois Urbana-Champaign.
U.S. Non-Provisional Patent Application: “Z(2-aminoadenosine) Base Incorporated RNA (guide RNA and mRNA) Increases CRISPR-Cas Editing Efficiency.” Inventors: Huimin Zhao, University of Illinois Urbana-Champaign.
2023 Filings
U.S. Patent Application: “Enhanced Extraction of Natural Products from Biomass.” Inventors: Vijay Singh, Shivali Banerjee, and Erik Sacks, University of Illinois Urbana-Champaign.
U.S. Non-Provisional Patent Application: “Methods and Compositions for Producing Plants having High Vegetative Fatty Acids.” Inventors: Ed Cahoon, Kiyoul Park, Truyen Quach, and Tom Clemente, University of Nebraska-Lincoln.
U.S. Non-Provisional and Provisional Patent Applications: “Metabolically Engineered Issatchenkia orientalis Strains for Succinic Acid Production.” Inventors: Huimin Zhao and Vinh Tran, University of Illinois Urbana-Champaign.
Invention Disclosure: “Semi-Abstracted Generative Adversarial Network.” Inventors: Andrew Leakey and Sebastian Varela, University of Illinois Urbana-Champaign.
U.S. Non-Provisional and Provisional Patent Applications: “Biostimulant Potential of a Yeast 2,3-Butanediol Fermentation Broth for Alleviation of Drought Stress of Plants”. Inventors: Yong-Su Jin, University of Illinois Urbana-Champaign.
Invention Disclosure: “COmputational Pipeline for Identification of neutral IntEgration Sites (CRISPR-COPIES).” Inventors: Huimin Zhao, University of Illinois Urbana-Champaign.
U.S. Patent: “Free Fatty Acid Separation And Recovery Using Resin.” Inventors: Vijay Singh, University of Illinois Urbana-Champaign.
Invention Disclosure: “Improved Water Use Efficiency Gene.” Inventors: Andrew Leakey, University of Illinois Urbana-Champaign.
2022 Filings
Invention Disclosure: “Highly Efficient and Scarless Assembly of DNA Molecules Using One-Pot Exonuclease Treatment and Phosphorylation.” Inventors: Huimin Zhao and Behnam Enghiad, University of Illinois Urbana-Champaign.
U.S. Provisional Patent: “Enhanced Extraction of Natural Products from Biomass.” Inventors: Vijay Singh, Shivali Banerjee, and Erik Sacks, University of Illinois Urbana-Champaign.
U.S. Provisional Patent Application: “Compositions and Methods for Suppression of Flowering in Sugarcane and Energycane.” Inventors: Fredy Altpeter and Baskaran Kannan, University of Florida.
U.S. Non-Provisional Patent Application: “Plant SWEET and Yeast MSF Transporter Capable of Transporting Different Sugars Simultaneously.” Inventors: Yong-Su Jin, Nurzhan Kuanyshev, Anshu Deewan, and Christopher Rao, University of Illinois Urbana-Champaign.
U.S. Non-Provisional Patent Application: “A DNAzyme-based Genome Engineering Method.” Inventors: Yi Lu and Mingkuan Lyu, University of Illinois Urbana-Champaign.
Invention Disclosure: “Cell-type Specific Genes to Enable the Spatial-Temporal Expression of Bioproducts in Grass Stems.” Inventors: Amy Marshall-Colon, Kankshita Swaminathan.
U.S. Non-Provisional Patent Application: “CropEYEs.” Inventors: Kaiyu Guan, University of Illinois Urbana-Champaign.
Invention Disclosure: “PlasmidMaker is a Versatile, Automated, and High Throughput end-to-end Platform for Plasmid Construction.” Inventors: Huimin Zhao, University of Illinois Urbana-Champaign.
2021 Filings
U.S. Non-Provisional and Provisional Patent Applications: “A CRISPR/Cas9-Based Tool for Genome Editing in Issatchenkia orientalis.” Inventors: Vinh Tran, Mingfeng Cao, Zia Fatma, and Huimin Zhao, University of Illinois Urbana-Champaign.
Invention Disclosure: “Chemical-Free Production of HMF, Furfurals, and Acetic Acid and a Consolidated Bioprocess Design to Recover High-value Platform Chemicals along with Bioethanol from Lignocellulosic Biomass.” Inventors: Vijay Singh and Shraddha Maitra, University of Illinois Urbana-Champaign.
Invention Disclosure: “Method for the Production of Sorghum with High Vegetative Triacylglycerols.” Inventors: Thomas E. Clemente, Kiyoul Park, Truyen Quach, and Edgar B. Cahoon, University of Nebraska-Lincoln.
Invention Disclosure: “A Thiol-mediated Update for Efficient Delivery of Antisense DNA and DNA Aptamers in Plants for Gene Silencing and Glucose Sensing”. Inventors: Yi Lu.
U.S. Non-Provisional and Provisional Patent Applications: “Methods for Assessing Agriculture Productivity and Sustainability.” Inventors: Kaiyu Guan, Bin Peng, Jian Peng, University of Illinois Urbana-Champaign.
2020 Filings
U.S. Provisional Patent Application: “Cells and Methods for Producing Methyl Ketones.” Inventors: Qiang Yan and Brian Pfleger, University of Wisconsin-Madison.
Invention Disclosure: “Photoenzymatic Synthesis of γ-Chiral Carbonyl Compounds.” Inventors: Huimin Zhao, Xiaoqiang Huang, Yajie Wang, and Guangde Jiang, University of Illinois Urbana-Champaign.
2019 Filings
U.S. Provisional Patent Application: “A CRISPR/Cas9 System for High Efficiency Gene Deletion in Rhodosporidium toruloides.” Inventors: John Carl Schultz, Mingfeng Cao, and Huimin Zhao, University of Illinois Urbana-Champaign.
Invention Disclosure: “A Genetic Toolbox for Metabolic Engineering of Issatchenkia orientalis.” Inventors: Huimin Zhao, Mingfeng Cao, Zia Fatma, Vinh Tran, and Xiaofei Song, University of Illinois Urbana-Champaign.
U.S. Provisional Patent Application: “Processing of Lipid-Producing Biomass for High Yields of Oils and Cellulosic Sugars for Biofuel Production.” Inventors: Deepak Kumar, Vijay Singh, and Yuyao Jia, University of Illinois Urbana-Champaign.
Invention Disclosure: “Methods for High-throughput Evaluation of Ligase Fidelity and Design Scheme for Highly Efficient, Scar-less Golden Gate Assembly and Point Mutation.” Inventors: Huimin Zhao, University of Illinois Urbana-Champaign.
2018 Filings
Invention Disclosure: “Cooperative Asymmetric Reactions Combining Photocatalysis and Enzymatic Catalysis.” Inventors: Huimin Zhao, John F. Hartwig, Yajie Wang, and Zachary C. Litman, University of Illinois Urbana-Champaign.
Invention Disclosure: “Use of CRISPER/Cas9 with Consensus Guide RNA to Reduce Alpha Prolamins for Digestibility and Lysine Improvements in Sorghum and Maize.” Inventors: David Holding and Thomas Clemente, University of Nebraska-Lincoln.