Adsorptive Separation and Recovery of Triacetic Acid Lactone from Fermentation Broth

Themes: Conversion, Sustainability

Keywords: Biomass Analytics, Economics


Singh, R.Bhagwat, S.S.Viswanathan, M.B.Cortés-Peña, Y.R.Eilts, K.K.McDonough, G.Cao, M.Guest, J.S.Zhao, H.Singh, V. Aug. 19, 2022. “Bioindustrial-Park–TAL” GitHub Repository.


Figure 1. Simplified block flow diagram depicting the biorefinery’s (A) conversion and (B) 465 separation processes. Acronyms in the figure denote solid/liquid separation (S/L separation), 466 corn steep liquor (CSL), and wastewater treatment (WWT). Some streams are not included for 467 figure clarity; the process flow diagram in the system report includes the full set of details 468 available in the online repository (BioSTEAM, 2020b).

Triacetic acid lactone (TAL) can be microbially produced and further chemically upgraded to several high-value chemicals. In this work, several acidic and basic ion-exchange resins and activated charcoal were evaluated for their ability to adsorb microbially produced TAL. Activated charcoal and a weak base resin, Dowex 66, showed similar TAL adsorption capacity of 0.18 ± 0.002 g/g. At 15% w/v activated charcoal, about 98% of TAL present in fermentation broth could be adsorbed. Further, ethanol washing allowed recovery of 72% of adsorbed TAL. A biorefinery producing TAL from sucrose was designed, simulated, and evaluated (through technoeconomic analysis) under uncertainty, for an estimated TAL minimum product selling price (MPSP) of $4.27/kg [$3.71−4.94/kg; 5th-95th percentiles] for the current state of technology and $2.83/kg [$2.46–3.29/kg] following potential near-term improvements to fermentation. Thus, this work provides an adsorptive process to recover microbially produced TAL that can be chemically upgraded to several industrial products.


Github – TAL Data and Code

Download (6.4MB) includes:

  • Adsorption Comparison
  • Resin Properties
  • Uncertain Parameters

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